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Product Info Summary
| SKU: | M01188 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | Flow Cytometry, IP, IHC |
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Product info
Product Name
Anti-Hu CD1c Purified Monoclonal Antibody
View all CD1c/BDCA-1 Antibodies
SKU/Catalog Number
M01188
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD1c Purified Monoclonal Antibody (Catalog# M01188). Tested in Flow Cytometry, IP, IHC application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD1c Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01188)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
L161
Isotype
Mouse IgG1 kappa
Immunogen
Human thymocytes. The mouse monoclonal antibody L161 recognizes an extracellular epitope of CD1c, (R7), a 43 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on cortical thymocytes (strongly), Langerhans cells, dendritic cells, B and some T cells.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01188 is reactive to CD1C in Human
Applications
M01188 is guaranteed for Flow Cytometry, IP, IHC Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
37.654kDa
Background of CD1c/BDCA-1
CD1c (also known as R7 or BDCA1) together with CD1a and b, belongs to group 1 of CD1 antigens. These non-classical MHC-like glycoproteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. The trafficking routes of the particular CD1 types differ and correspond to their ability to bind and present different groups of antigens. CD1c is unique in its ability to present e.g. mycobacterial phosphoketides and polyisoprenoids. CD1c is the only CD1 isoform that has been shown to interact both with alpha/beta and gamma/delta T cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml.
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For CD1C (Source: Uniprot.org, NCBI)
Gene Name
CD1C
Full Name
T-cell surface glycoprotein CD1c
Weight
37.654kDa
Alternative Names
BDCA1; BDCA-1; c polypeptide; CD1; CD1A; CD1c antigen; CD1c molecule; CD1c; cortical thymocyte antigen CD1C; differentiation antigen CD1-alpha-3; R7; T-cell surface glycoprotein CD1c CD1C BDCA1, CD1, CD1A, R7 CD1c molecule T-cell surface glycoprotein CD1c|CD1C antigen, c polypeptide|cortical thymocyte antigen CD1C|differentiation antigen CD1-alpha-3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD1C, check out the CD1C Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD1C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD1c Purified Monoclonal Antibody (M01188)
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